Dieumerci Mbokani will be in the squad and could make his debut for Hull City, who have suffered no new injuries since Matchweek 4.
Petr Cech will return in goal for Arsenal after David Ospina played in the UEFA Champions League in midweek, while Theo Walcott could return from a knee problem.
Aaron Ramsey remains out of contention and Olivier Giroud will have a minor toe injury assessed.
Did you know?
Since beating Arsenal in their first Premier League meeting with them in September 2008, Hull City have lost six of the last seven meetings with the Gunners (D1).
Alexis Sanchez has scored four goals and assisted two more in four previous matches against the Tigers across all competitions.
This is Hull’s best start to a Premier League campaign after four matches. They also had seven points in 2008/09, but had a negative goal difference.
Santi Cazorla’s last seven PL goals have been from the penalty spot (tied with Danny Murphy, Jan Mobly and Mikel Arteta). One more will set a record run.
What the managers say
Mike Phelan: "It will be a tough game against a top team full of excellent players, but the spotlight will be on Arsenal. We’ll be up for this challenge."
See: 'We'll relish Arsenal challenge'
Arsene Wenger: “He (Phelan) is doing very well. He’s a real football man who has given some stability to Hull.”
