Sheffield United are destined to finish bottom regardless of the result but will be hoping to break the 20-goal barrier by finding the net.
Burnley can finish as high as 15th if other results go their way.
Team news
Did you know?
Sheff Utd have won one of their last seven league matches against Burnley (D2 L4), a 3-0 victory in this exact fixture last season.
Sheff Utd have scored 19 PL goals in 2020/21 and could become the first ever top-flight team to fail to score at least 20 goals in a full season.
Burnley are aiming to complete the double over the Blades for just the third time, previously doing so in 1921/22 and 2008/09.
Without goalkeeper Nick Pope, Burnley have lost all five PL contests this season, conceding 17 goals at an average of 3.4 per match.
Match officials
Referee: Kevin Friend. Assistants: Simon Beck, Andrew Fox. Fourth official: Geoff Eltringham. VAR: Lee Mason. Assistant VAR: Matthew Wilkes.