Arsenal are looking to claim their third win in four PL matches while Cardiff City are aiming for their second win in eight.
Team news
Arsenal's defence will be without Sokratis (ankle), Hector Bellerin and Rob Holding (both knee), while Laurent Koscielny (jaw) is also a doubt.
Nacho Monreal (ankle) and Konstantino Mavropanos (groin) are back in contention after lengthy spells on the sidelines.
Henrikh Mkhitaryan (foot) is back in training but Danny Welbeck (knee) is out.
Cardiff are likely to be without defender Sean Morrison, who has had an operation to remove his appendix.
Jazz Richards (fitness) and Kenneth Zohore (thigh) are doubts but Harry Arter (groin) could return.
Did you know?
Arsenal have won all three of their Premier League meetings with Cardiff, scoring eight goals and conceding two.
Six of Arsenal's eight Premier League goals against Cardiff have come in the second half, with five of those coming in the last 10 minutes.
Cardiff are the only side yet to be leading at half-time in any of their Premier League fixtures this season.
Arsenal are unbeaten in their last 23 home Premier League fixtures against promoted sides since a 0-1 loss against Newcastle United in November 2010.
Referee: Mike Dean
Assistants: Darren Cann, Dan Robathan
Fourth official: Kevin Friend