Team news
Did you know?
Southampton have lost only three of their last 43 Premier League home matches against sides starting the day in the bottom three (W29 D11), winning each of their last three.
Saints have kept a clean sheet in six of their last seven meetings with Fulham in all competitions.
Fulham are aiming to avoid defeat in their first match after being relegated for the third time in a row, having drawn 2-2 with Crystal Palace in 2013/14 and beaten Everton 2-0 in 2018/19.
The Cottagers have scored first in nine PL away matches this season, their most ever in a campaign in the competition. But they have gone on to win just 33 per cent of those matches (W3 D5 L1).
Match officials
Referee: Craig Pawson. Assistants: Ian Hussin, Richard West. Fourth official: Robert Jones. VAR: David Coote. Assistant VAR: Neil Davies.