Fulham handed Everton's Under-23s their first defeat of the season as they beat the holders 2-1 in the Premier League Cup.
Luca de la Torre gave the hosts the lead at Motspur Park 10 minutes before half-time.
Everton levelled after the break as half-time substitutes Manasse Mampala and Kyle John combined for the latter to score.
But Fulham recovered to find a winner as Nicolas Santos-Clase squared for Sonny Hilton, pictured, to convert.
Fulham top Group B with Plymouth Argyle and Watford on one point each.
See: Fulham report | Everton report
Liverpool 3-2 Wigan
Sixteen-year-old Tom Hill scored on his debut for the Liverpool Under-23s in a hard-fought 3-2 victory over Wigan Athletic.
Elijah Dixon-Bonner put the Reds 2-0 up with both goals inside the opening 15 minutes, but Joe Gelhardt pulled a goal back for Wigan.
Hill restored the two-goal lead, only for Gelhardt to score his second.
Wigan piled the pressure on but goalkeeper Caoimhin Kelleher helped hold them at bay to earn the Group F victory.
See: Liverpool report
Middlesbrough 1-1 Burnley
A late Middlesbrough penalty denied Burnley an opening win to their cup campaign.
Scott Wilson had given the Clarets an 11th-minute lead in their Group G tie at Bishop Auckland’s Heritage Park.
But, three minutes from time, Boro were awarded a penalty and captain Ben Liddle stepped up to ensure the points were shared.