Watford have announced the departure of their head coach Quique Sanchez Flores.
The 54-year-old returned for his second spell at the club on 7 September, having previously overseen their 2015/16 campaign.
The Spaniard took charge of 10 league matches and led his side to draws against Arsenal and Tottenham Hotspur.
However, Saturday’s 2-1 defeat by Southampton leaves Watford bottom of the table with eight points from 14 matches, six points adrift of 17th-placed Everton.
Chairman and chief executive Scott Duxbury told the club's official website: "Quique is a man of great integrity and it was clear how much he wanted to have a positive impact, but ultimately results have dictated our decision.
"The appointment of a new head coach is imminent, and with nearly two-thirds of the season remaining, we will provide all the support necessary to make the coming months successful."
Watford are next in Premier League action at Leicester City on 4 December.