Tottenham Hotspur are seeking a return to winning ways after a run of three straight victories was ended by last weekend's defeat at Chelsea.
Wolverhampton Wanderers would overtake their hosts if they are triumphant in north London.
Team news
Harry Kane (hamstring) has started on-field rehabilitation but is not available for selection.
Ryan Sessegnon (hip), Moussa Sissoko (knee) and Son Heung-min (arm) are ruled out but Juan Foyth (groin) may be in contention.
Did you know?
Spurs have lost just one of their last seven league encounters with Wolves, although that defeat came when they last hosted Nuno Espirito Santo's side in 2018/19.
The north London club are looking to secure a third consecutive league win at Tottenham Hotspur Stadium for the first time since their first three such matches at the ground in April 2019.
Since their promotion in 2018, Wolves are unbeaten in their eight Premier League trips to London (W3 D5), their longest top-flight undefeated run in the capital since a sequence of 11 between 1972 and 1974.
Raul Jimenez has scored 12 goals in 27 Premier League appearances this season, just one fewer than he managed in 38 matches last term.
Match officials
Referee: Stuart Attwell. Assistants: Marc Perry, Simon Long. Fourth official: Kevin Friend. VAR: Simon Hooper. Assistant VAR: Mark Scholes.