Everton are aiming to halt a three-match winless run and keep their hopes of a top-half finish alive.
Aston Villa beat Crystal Palace last time out, and another victory would take them one point behind 17th-placed Watford in the relegation battle.
Team news
Mason Holgate (shin) and Andre Gomes (ankle) could return for Everton, while Yerry Mina (muscular problem) will be assessed.
Kortney Hause (rib) is a doubt for Villa, while Neil Taylor is struggling with a hamstring issue. Tom Heaton, Wesley and Bjorn Engels are long-term absentees.
Did you know?
Everton v Aston Villa will become the seventh Premier League fixture to be played on all seven days of the week. And a win for the Villans would make them the second team to beat an opponent on every day of the week in the competition, after Manchester United against Villa.
Everton have won their last three home league meetings with Villa, their best such run against them since the five straight victories at Goodison Park between 1964 and 1975.
The Toffees can achieve an 11-match unbeaten run in Premier League home matches for the first time since December 2016. Only Liverpool are on a longer current run, with their 58-match sequence.
Villa are looking to secure their first league double over Everton since 2000/01, following their 2-0 win in August's reverse fixture.
Match officials
Referee: Anthony Taylor. Assistants: Gary Beswick, Adam Nunn. Fourth official: Darren England. Replacement official: James Mainwaring. VAR: Chris Kavanagh. Assistant VAR: Dan Cook.