Swansea City are likely to again be without Federico Fernandez and Ki Sung-yueng, who both have toe injuries.
Gaston Ramirez (foot) may be fit to return for Middlesbrough, having missed Wednesday's match against Liverpool, but Cristhian Stuani (foot) is still out.
Middlesbrough manager Aitor Karanka expects Calum Chambers (shoulder) and George Friend (knee) to be fit after he picked up a minor injury in midweek.
Did you know?
This will be the first top-flight meeting between these two clubs since May 1982. In fact, 1981/82 was the only other season that these two clubs played in the top flight together.
Only Southampton's St. Mary's Stadium (13 goals) has witnessed fewer Premier League goals this season than Middlesbrough’s Riverside Stadium (16).
Swansea have won each of their last three competitive meetings with Middlesbrough, all by a one-goal margin (1-0, 4-3, 1-0).
The Swans have conceded 34 league goals this season – 10 more than they have after 16 matches in any previous Premier League season (24 in 2015/16 after 16 matches).
What the managers say
Bob Bradley: "You look at the table and games against teams that are closer to you do take on more importance, but I think we can all agree that every game is massive for us right now."
See: Time to start a run, says Bradley
Aitor Karanka: "Swansea score goals but we have to take advantage because they concede as well."
See: Middlesbrough's match pack | Aitor Karanka's injury update