Tottenham Hotspur’s Harry Kane (£11.2m) has made a rapid recovery from an ankle injury in time for against Watford at White Hart Lane.
But manager Mauricio Pochettino is uncertain whether to start the striker on Saturday, with Son Heung-min (£7.0m) or Vincent Janssen (£7.5m) also being considered for the role up front.
Watford arrive in north London with a string of absentees in defence.
Goalkeeper Heurelho Gomes (£4.9m) is doubtful, while Younes Kaboul (£4.4m) and Sebastian Prodl (£4.4m) are injured and Miguel Britos (£4.3m) serves the first of a two-match suspension.
Liverpool have mounting concerns in attack for their trip to Stoke City, with Philippe Coutinho (£8.4m) struggling to overcome the illness that forced him off against AFC Bournemouth in midweek.
The Brazilian had produced back-to-back goals for the first time this season by scoring on Wednesday, inspiring 28,000+ Fantasy Premier League managers to transfer him in for Gameweek 32.
Manager Jurgen Klopp may look to Daniel Sturridge (£9.6m) as part of his front three should Coutinho fail to recover.
An in-depth fitness update on Coutinho, Henderson and Lallana: https://t.co/ZVyV801fry pic.twitter.com/04tq4iWRaX
— Liverpool FC (@LFC) April 7, 2017
Chelsea head coach Antonio Conte is expected to shuffle his side after the versatile Victor Moses (£5.5m) was passed fit for a trip to AFC Bournemouth.
Cesar Azpilicueta (£6.4m) started as right wing-back in the midweek victory over Manchester City, but the Spaniard could return to his role in the Blues’ back three to allow for Moses’ return.
Meanwhile, Everton and Leicester City have key absentees in defence for their match at Goodison Park.
Ashley Williams (£5.2m) will serve a one-match ban for Everton, while Leicester are without influential captain Wes Morgan (£4.7m), who has a back problem.
Leicester have recorded back-to-back clean sheets under Craig Shakespeare and will look to silence Romelu Lukaku (£10.4m), who has 10 goals in his last six outings at Goodison Park.
Hull City face a testing trip to Manchester City without Harry Maguire (£4.4m), who has a knee complaint.
An ever-present under head coach Marco Silva, Maguire’s absence will likely mean a start for Michael Dawson (£4.2m) or Curtis Davies (£4.9m), a shuffle that could promote the prospects of Sergio Aguero (£12.7m).
Manolo Gabbiadini (£6.7m) remains a doubt for Southampton’s trip to West Bromwich Albion with his groin injury.
Having missed the last two matches, the Italian has been sold by 28,000+ FPL managers in the Gameweek. Shane Long (£6.1m) and Jay Rodriguez (£6.0m) are vying for the lone forward role in his absence.
Michail Antonio (£6.8m) and Andy Carroll (£6.3m) are expected to recover from illness and a groin problem respectively in time for West Ham United’s home match with Swansea City.
Carroll has five goals and three assists in his last six appearances versus Swansea and has scored more goals (six) against them than against any Premier League side.
Paul Clement’s men have their own concerns up front, with Fernando Llorente (£6.4m) hoping for a return having trained this week.
Over 57,000 FPL managers have sold the Spaniard since Tuesday evening’s deadline, more than any other forward.