Tottenham Hotspur are closing in on an impressive winning home sequence, with AFC Bournemouth next up at White Hart Lane, while Sergio Aguero is eyeing an impressive goalscoring run of his own against Southampton .
To see key stats from all 10 matches this weekend, see below.
(All kick-offs 3pm BST unless stated otherwise)
Saturday 15 April
12.30pm Tottenham Hotspur v AFC Bournemouth
Spurs have won 11 home PL matches in a row, their best winning streak at White Hart Lane since October 1987 (14)
Crystal Palace v Leicester City
The Eagles can claim a fourth straight league victory at Selhurst Park for the first time since December 1990
Everton v Burnley
In 2017 Romelu Lukaku (13 goals from 42 shots) has scored more PL goals than Saturday's visitors (11 goals from 146 shots)
Stoke City v Hull City
Since Marco Silva’s appointment on 5 January, Hull have won the most points from losing positions in the top flight (nine)
Sunderland v West Ham United
Jermain Defoe has scored six goals in 15 PL matches v West Ham, but has yet to score against his old club in three outings for Sunderland
Watford v Swansea City
A league-high 24% of the shots that Swansea have attempted in the PL this season have been from headers. They have also attempted the most headed shots (84)
5:30pm Southampton v Manchester City
Sergio Aguero has scored in 11 successive PL appearances in the month of April (14 goals) and he has found the net in four successive appearances overall
Sunday 16 April
1.30pm West Bromwich Albion v Liverpool
Philippe Coutinho is aiming to score in four successive Premier League matches for the first time
4pm Manchester United v Chelsea
Antonio Conte could become the fourth Chelsea manager to record a PL double over the Red Devils, after Glenn Hoddle (1993/94), Jose Mourinho (2004/05) and Carlo Ancelotti (2009/10)
Monday 17 April
8pm Middlesbrough v Arsenal
Arsenal have lost four successive PL away matches for the first time since April 1995, before Arsene Wenger’s reign started