Here's what to look out for over the next week, with clubs in midweek EFL Cup action, while the Premier League returns with five matches, including Manchester United versus Tottenham Hotspur.
Tuesday
Five-time EFL Cup winners Chelsea make the trip to Middlesbrough for the semi-final first leg.
This encounter will bring back memories of when the two sides met in the final of this competition in 1998, with the Blues going on to lift the cup thanks to two stoppage-time goals.
The second leg takes place at Stamford Bridge on Tuesday 23 January.
Wednesday
The second EFL Cup semi-final first leg match pits Liverpool against Fulham in an all-Premier League tie.
These two met at the quarter-final stage of the competition during the 2000/01 season, with Liverpool winning 3-0 en route to eventually triumphing in the final.
The second leg is set for Wednesday 24 January at Craven Cottage.
Thursday
Burnley manager Vincent Kompany and Luton Town boss Rob Edwards will hold press conferences ahead of Friday's rescheduled fixture.
Friday
Matchweek 21 begins with Burnley hosting Luton at 19:45 GMT.
Five Matchweek 21 matches will be played over the coming weekend and the other five on the weekend commencing 20 January due to the mid-season player break.
Several managers will also hold press conferences as they provide updates ahead of the weekend's Premier League fixtures.
There's an early deadline in Fantasy Premier League this week, with FPL managers needing to confirm their teams before 18:15 GMT.
The Asian Cup also gets under way, with hosts Qatar taking on Lebanon.
Saturday
In the first of two Saturday fixtures, Chelsea entertain Fulham in a west London derby at 12:30 GMT.
Following this, Newcastle United host champions Manchester City at 17:30 GMT.
The Africa Cup on Nations starts at 20:00 GMT when host nation Ivory Coast face Guinea-Bissau.
Sunday
Two more fixtures take place, as Everton welcome Aston Villa at 14:00 GMT, with the Toffees aiming to avoid a fourth consecutive Premier League defeat.
The final match of the weekend at 16:30 GMT is the mouthwatering contest at Old Trafford, where Spurs are the visitors.