Tottenham Hotspur have suffered a fresh double injury blow, with full-backs Pedro Porro and Destiny Udogie ruled out of their match against Wolverhampton Wanderers on Saturday.
Tottenham Hotspur head coach Ange Postecoglou revealed that both defenders will be unavailable against Wolves, but added that neither injury is serious.
Team news | Spurs vs Wolves | Fresh injury concerns in blow to defence
"We've had a couple of setbacks this week," Postecoglou said on the club's official website.
"Destiny, in last week's game, jarred something in his knee a little bit. I don't think it's anything too serious, but he'll miss tomorrow and hopefully without a game next week that's all he'll miss.
"Pedro picked up a strain in training and again he'll miss tomorrow, maybe a couple of weeks.
"It doesn't change the way we play but I think I've said in the past, a player brings their own sort of unique ability to each position.
"The structure won't change and the way we set up won't change, but different players bring different attributes. Pedro and Destiny have been outstanding for us this year.
"Pedro has pretty much played every game apart from the first one where he didn't start. Destiny every time he has been out there for us has been really important.
"They're both improving, but as I said, they're missing now and there will be an opportunity for a couple of other guys to come in and make sure we maintain the levels we've set so far."
Both players have been crucial to Spurs this season, who currently sit in fourth place in the table.
Since making his first start of the season against Manchester United in Matchweek 2, Porro has played in every league match since and provided seven assists.
Meanwhile, Udogie has impressed in his debut season at the club after returning on loan from Udinese, producing two goals and three assists in 21 league appearances.
What does it mean for FPL managers?
Owners of Spurs defenders Pedro Porro (£5.8m) and Destiny Udogie (£4.9m) should look to Manchester City’s Nathan Ake (£5.1m) as their top replacement.
In addition to being ruled out against Wolves, Porro and Udogie are also without a fixture in Blank Gameweek 26 (BGW26).
Ake, by contrast, has three matches in that period. Man City have a Double Gameweek 25 (DGW25) at home to both Chelsea and Brentford, and then visit AFC Bournemouth in BGW26.
Managers should also factor in their chip strategies for the upcoming period before moving on the Spurs pair, as both are expected to be absent for a short period of time.
Spurs are currently one of only six sides who have a match scheduled in Blank Gameweek 29 (BGW29) and their players are likely to be key targets.
Managers who are planning to play a Free Hit chip in BGW26, for example, could simply bench Porro or Udogie in DGW25 and keep them in their squads ahead of BGW29.