Here's what to look out for over the next seven days, including a UEFA Europa Conference League semi-final and another huge weekend of Premier League action, including Liverpool v Tottenham Hotspur.
Wednesday
Mauricio Pochettino and Ange Postecoglou will provide the latest team news updates ahead of Chelsea's home encounter with Spurs on Thursday.
Aston Villa head coach Unai Emery will speak to the media prior to their Europa Conference League semi-final first-leg meeting with Olympiacos.
Thursday
Matchweek 35 concludes with a London derby as Chelsea take on Spurs.
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The Blues are aiming to complete a league double over Spurs, having beaten them 4-1 in one of the most memorable matches of the season so far last November.
In the Europa Conference League, Villa host Olympiacos. Emery's side will take confidence from their form at Villa Park in the competition, where they have won all six home matches this season.
Rob Edwards and Sean Dyche will hold their press conferences ahead of Friday's match between Luton Town and Everton, while several managers will also provide updates ahead of the weekend's Premier League fixtures.
The shortlists for the April Player of the Month, Manager of the Month, Goal of the Month and Save of the Month awards will also be revealed.
Friday
The Fantasy Premier League deadline will be at 18:30 BST.
Luton welcome Everton to Kenilworth Road in the first fixture of Matchweek 36. A win for the Hatters would move them out of the bottom three, while the Toffees are seeking a fourth consecutive victory.
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The remaining Premier League managers will hold their press conferences, providing the latest team news.
Saturday
Matchweek 36 continues with title-chasing Arsenal hosting AFC Bournemouth at 12:30 BST.
Following this, there are three 15:00 BST kick-offs, before Manchester City take on Wolverhampton Wanderers at the Etihad Stadium (17:30 BST).
Sunday
Villa make the trip to Brighton & Hove Albion, while West Ham United visit Chelsea, with both fixtures starting at 14:00 BST.
Liverpool face Spurs in the penultimate home match of Jurgen Klopp's tenure at 16:30 BST.