Frank Lampard's first Premier League match in charge of Chelsea comes away against Manchester United, who are starting their first full season under Ole Gunnar Solskjaer.
Team news
Aaron Wan-Bissaka, Harry Maguire and Daniel James are all available to make their Man Utd debuts.
Paul Pogba (back) is fit, but Alexis Sanchez is unlikely to feature after sustaining an injury with Chile at the Copa America. Eric Bailly and Tim Fosu-Mensah remain sidelined.
Frank Lampard confirmed that N'Golo Kante is fit, but will be assessed ahead of Sunday's match.
Antonio Rudiger has been back in training, while Willian remains a doubt for Chelsea.
Did you know?
Man Utd and Chelsea have won more opening-weekend fixtures than any other sides in the Premier League, with 18 and 17 victories respectively.
When kicking off a Premier League campaign at home, Man Utd have lost only one of their last 26 matches (W19 D6), a 2-1 defeat to Swansea City in 2014/15.
Chelsea’s six Premier League wins at Old Trafford have all come under different managers – Glenn Hoddle, Ruud Gullit, Claudio Ranieri, Jose Mourinho, Carlo Ancelotti and Rafael Benitez. Five of those six victories came in the manager's first league visit to the stadium with the Blues, with Ranieri the exception.
This will be the first competitive meeting between Man Utd and Chelsea where both managers also previously played for their respective clubs.
Referee: Anthony Taylor
Assistants: Gary Beswick, Adam Nunn
Fourth official: Lee Mason
VAR: Stuart Attwell
Assistant VAR: Stephen Child