If Liverpool avoid defeat against Leicester City at Anfield on Sunday, not only will they strengthen their hopes of retaining the title but they will beat a club record that has stood for 40 years.
For more on this and all the must-know stats for Matchweek 9, read on. To check out the head-to-head records, click on the fixtures.
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Timo Werner can be the first player since Didier Drogba back in 2009 to score in five straight matches in all competitions for Chelsea.
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Jack Grealish is looking to score against Brighton & Hove Albion for a fifth consecutive match.
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Tottenham Hotspur are on the longest active unbeaten run in the Premier League (W5 D2).
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West Bromwich Albion can win successive league matches against Manchester United for the first time since 1980.
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Everton are aiming to win three Premier League matches in a row in London for the first time.
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West Ham United are hoping to extend their run of 11 matches unbeaten against teams starting the day bottom of the league.
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Leeds United are seeking their first win in eight matches in all competitions against Arsenal (D1 L6) since a 3-2 victory at Highbury in May 2003.
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If Liverpool avoid defeat, they will go a club-record 64 home top-flight matches unbeaten, eclipsing a run that was ended in 1980 by Leicester.
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The last time these teams met Burnley won to end a run of four straight defeats by Crystal Palace.
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Southampton are targeting a fourth successive Premier League win for the first time since May 2016.