A trip to Burnley gives Pierre-Emerick Aubameyang (£11.3m) the chance to extend his strong run of form in Fantasy Premier League.
The Arsenal star, classified as a midfielder in FPL, has scored seven goals in his last five starts in all competitions.
That run includes his season-high haul of 20 points against Leeds United in Gameweek 24.
Aubameyang also has a prolific record against his weekend hosts, scoring seven goals six meetings with Burnley.
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Burnley, meanwhile, have struggled defensively at Turf Moor recently, claiming a single clean sheet in their last seven home matches.
Aubameyang earns a place in a Scout Selection that lines up in a 3-4-3 formation, with Manchester City's Kevin De Bruyne (£11.8m) handed the armband and team-mate Ruben Dias (£6.1m) named vice-captain.
Sam Johnstone (WBA) £4.5m
A home encounter against Newcastle United’s injury-hit attack can help the West Bromwich Albion goalkeeper continue his improving run of returns.
Johnstone has 19 points in his last three outings, combining two clean sheets with two save points and three bonus points.
Trent Alexander-Arnold (LIV) £7.4m
The Liverpool right-back's nine shots and 11 chances created over the last four Gameweeks both rank among the top two defenders in Fantasy.
He can bring in points at both ends of the pitch at home to a Fulham side with only four goals in their last seven matches.
Ruben Dias (MCI) £6.1m
The Portuguese appears to offer the most secure route into Manchester City’s defence for their Double Gameweek 27 against Manchester United and Southampton.
Dias has started 24 of their last 25 matches, producing one goal, one assist and 14 clean sheets.
Jannik Vestergaard (SOU) £4.7m
Southampton’s centre-back has been a major goal threat in recent matches ahead of their Double Gameweek 27 against Sheffield United and Man City.
His total of seven shots in the penalty area across the last four Gameweeks ranks joint-top among defenders in Fantasy.
Kevin De Bruyne (MCI) £11.8m
Back-to-back fixtures at the Etihad Stadium lifts the Belgian’s captaincy credentials.
At home, De Bruyne’s 37 shots and 29 chances created are both team-leading totals for Man City.
Pierre-Emerick Aubameyang (ARS) £11.3m
An ownership of only 6.9 per cent highlights his appeal as a huge differential against Burnley.
Son Heung-min (TOT) £9.5m
The South Korean has been Tottenham Hotspur’s most explosive player in Fantasy when playing at home this season.
Son has produced six double-figure hauls at home, twice the total of any team-mate, ahead of a visit from Crystal Palace.
Ilkay Gundogan (MCI) £6.2m
Having featured as a substitute against Wolverhampton Wanderers in midweek, Gundogan will be fully refreshed for Man City’s two matches.
His average of 6.3 points per match is more than any other Man City midfielder or forward.
Danny Ings (SOU) £8.4m
The forward looks to be the Southampton player most likely to score or assist in their Double Gameweek.
When selected this season, Ings has been involved in a team-leading 44 per cent of Southampton's goals.
Patrick Bamford (LEE) £6.8m
The Leeds United forward's form in away matches will pose big problems for West Ham United on Monday.
Away from home, Bamford’s 46 shots and 38 shots in the box are more than any other player in 2020/21 FPL.
Michail Antonio (WHU) £6.5m
The forward has produced four goals and three assists in eight appearances since returning to West Ham's starting XI.
Antonio can thrive against a Leeds defence who have conceded 27 away goals, the second-most in the Premier League.
Also in this series
Part 1: GW27 Kings to watch: Antonio has form and fixture to thrive
Part 2: GW27 Differentials: Jesus can build on midweek brace
Part 3: GW27 Captains: Rest makes Gundogan a top choice
Part 4: Who to captain in GW27? What the experts say
Remember, the Gameweek 27 deadline is at 11:00 GMT on Saturday 6 March.