Manchester United manager Erik ten Hag says he does not know the extent of the injury suffered by Antony but that it looks like a "serious" problem.
Antony was taken off on a stretcher with an apparent ankle injury following a challenge from Trevoh Chalobah in Thursday's 4-1 win over Chelsea.
"I can tell you it is serious but we have to wait a minimum [of] 24 hours, then we know probably more about the status of the injury," Ten Hag revealed via the club's official website.
Luke Shaw was also taken off at half-time but Ten Hag is more hopeful about his left-back.
"We have to see," he added. "I don't think it's too bad but we have to wait 24 hours. We'll have a diagnosis and we will know more."
Man Utd's remaining matches
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While Man Utd confirmed a top-four finish and a return to the UEFA Champions League with their win on Thursday, the injuries are a blow to their hopes of winning this season's FA Cup.
They face Manchester City in the final on Saturday 3 June.
Antony and Shaw's PL stats
| Antony | Shaw | ||
| Appearances | 25 | Appearances | 31 |
|---|---|---|---|
| Goals | 4 | Goals | 1 |
| Assists | 2 | Assists | 2 |
| Chances created | 28 | Chances created | 34 |
| Succ. dribbles | 33 | Tackles | 55 |