Here's what to look out for over the next week, with one more fixture remaining in Matchweek 9, eight clubs playing in Europe, and another big weekend of Premier League action ahead, concluding with the HUGE Manchester derby between Manchester United and Manchester City.
Monday
Tottenham Hotspur welcome Fulham in the final fixture of Matchweek 9 at 20:00 BST knowing a victory would move Ange Postecoglou's side back to the top of the table.
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Spurs have an impressive record in matches played on Monday, having lost just one of their last 16 encounters played on that day, which came back in October 2018.
Arsenal manager Mikel Arteta and Man Utd boss Erik ten Hag will hold their respective press conferences ahead of Tuesday's UEFA Champions League matches.
Tuesday
In the Champions League, Arsenal travel to Spain to take on Sevilla and will hope to bounce back from their last match in the competition, where they were beaten 2-1 at Lens.
Man Utd have lost their opening two contests in Europe this season, so a first victory in Group A when they host Copenhagen will be crucial to their hopes of qualification for the round of 16.
Both matches kick off at 20:00 BST.
Pep Guardiola and Eddie Howe will hold their press conferences ahead of Man City and Newcastle United's matches in the same competition.
Wednesday
Newcastle are again in action at St James' Park, this time against Borussia Dortmund, and will hope for a repeat showing from their last Champions League home match, where they beat French giants Paris Saint-Germain 4-1.
Man City have triumphed in both of their Group G matches, and the reigning European champions now travel to Young Boys in Switzerland.
Both matches kick off at 20:00 BST.
Thursday
In the UEFA Europa League, West Ham United travel to Greece to face Olympiacos at 17:45 BST, while Brighton & Hove Albion host Ajax at 20:00 BST.
Liverpool, who have won both of their Europa League matches so far, return to Anfield as they entertain Toulouse at 20:00 BST.
In the UEFA Europa Conference League, Aston Villa will target a second successive win when they visit AZ Alkmaar at 17:45 BST.
Several managers will also hold press conferences as they provide updates ahead of the weekend's Premier League fixtures.
Friday
The remaining Premier League managers will hold their press conferences, providing the latest team news.
There's an early deadline in Fantasy Premier League this week, with FPL managers needing to make their transfers and confirm their line-up before 18:30 BST.
Matchweek 10 then begins with a second consecutive London derby for Spurs, as they travel to Selhurst Park to face Crystal Palace at 20:00 BST.
Saturday
In the first of four Saturday fixtures, Chelsea welcome Brentford in a west London derby at Stamford Bridge, which kicks off at 12:30 BST.
Following this, there will be two 15:00 BST kick-offs, before Wolverhampton Wanderers host Newcastle at 17:30 BST.
Sunday
There are a bumper FIVE matches taking place, featuring several sides who were in midweek European action. There are home encounters for West Ham, Villa, Brighton and Liverpool, with the Hammers welcoming Everton to London Stadium in the first match of the day at 13:00 GMT.
The final fixture of Matchweek 10 is one of the most anticipated of the season, as Man Utd host Man City at 15:30 GMT.
