West Ham United will assess the fitness of defender Arthur Masuaku (foot) and striker Andy Carroll (groin).
Forward Diafra Sakho (back) has been ruled out for the season.
Tottenham Hotspur left-back Danny Rose (knee) remains out but is due to return to full training next week.
Did you know?
West Ham United could win back-to-back home matches against Tottenham Hotspur in consecutive seasons for the first time since 1998/99 and 1999/00.
If Spurs win this match they will have recorded their most victories in a league campaign since 1966/67 (24).
Manuel Lanzini has scored 13 Premier League goals, eight of which have come in 13 London derby appearances (62%).
Harry Kane has five goals in his last five PL matches against West Ham and has scored 18 goals in his last 20 appearances against opposition from London.
What the managers say
Slaven Bilic: "Chelsea deserve to be on top, because they didn't have a hole in their season, but Spurs are playing the best football."
Mauricio Pochettino: "Every game is a must-win because to be alive in the race always win, win, win, win. If we don’t it will be difficult to catch Chelsea."
