Here's what to look out for over the next week, with clubs playing midweek FA Cup third-round replays, while the Premier League continues with four matches, including Arsenal versus Crystal Palace.
Tuesday
The FA Cup third-round replays begin with Wolverhampton Wanderers hosting Brentford (19:30 GMT), with the winners earning a trip to Championship side West Bromwich Albion in the fourth round.
Meanwhile, Luton Town travel north to face Bolton Wanderers (19:45 GMT), aiming to set up a trip to Everton or Crystal Palace in the next round. West Ham United visit Bristol City (19:45 GMT) knowing victory would give them a home tie in the fourth round, against Nottingham Forest or Blackpool.
At AFCON, Burkina Faso (14:00 GMT), Tunisia (17:00 GMT), and Mali (20:00 GMT) will play their opening group matches, with AFC Bournemouth’s Dango Outtara and Spurs' Yves Bissouma among the stars set to feature.
Wednesday
The FA Cup third-round replays continue, with Everton taking on Palace, while Nott'm Forest visit Blackpool (both 19:45 GMT).
There is more AFCON action as Morocco (17:00 GMT) and DR Congo (20:00 GMT) begin their campaigns, with Sofyan Amrabat and Yoane Wissa in contention to line up for each country respectively.
Thursday
There will be two heavyweight duels at AFCON as host nation Ivory Coast take on Nigeria (17:00 GMT), before at 20:00 GMT Mohamed Salah's Egypt face a Ghana team who have Mohammed Kudus, Jordan Ayew and Antoine Semenyo in their ranks. With both sides failing to win their first match, this Group B contest will be crucial.
Friday
Several managers will be holding their press conferences as they provide updates ahead of the weekend's Premier League action.
A Japan squad featuring Wataru Endo, Kaoru Mitoma and Takehiro Tomiyasu play Iraq in the Asian Cup (11:30 GMT), while there are three more matches in AFCON, including Senegal versus Cameroon (17:00 GMT).
Saturday
In the first of two Saturday fixtures, we begin with a London derby between Arsenal and Crystal Palace at Emirates Stadium at 12:30 GMT.
Following this, Brentford host Nott'm Forest at 17:30 GMT, with Ivan Toney in line to make his first appearance of the season following his ban.
Elsewhere, South Korea face Jordan in the Asian Cup. In AFCON, Algeria go up against Burkina Faso and Tunisia take on Mali.
Sunday
Two more fixtures in the Premier League take place as Sheffield United host West Ham at 14:00 GMT.
Then at Vitality Stadium league leaders Liverpool face Bournemouth at 16:30 GMT.
There is more AFCON action with three matches taking place, including Morocco versus DR Congo.