Refreshed from a two-week international break, the latest Fantasy Challenge focuses on defensive success, where clean sheets are worth DOUBLE points.
Armed with a £30.0m budget to select a 5-a-side team, the only useable formation involves two goalkeepers and three defenders.
Here, The Scout pinpoints the best picks in the remaining matches.
Sunday
14:00 BST Fantasy Challenge deadline
Spurs v Arsenal
Arsenal had a watertight defence last season, although the north London derbies ended 2-2 and 3-2. They enter this one without the suspended Declan Rice (£6.3m) and strong availability doubts over Martin Odegaard (£8.3m), which perhaps weakens their clean sheet prospects.
So, targeting defenders with attacking potential may be the strategy for this fixture.
Gabriel Magalhaes (£6.0m) is known for his set-piece threat while Spurs’ Pedro Porro (£5.5m) had six shots in Gameweek 3.
16:30 BST Fantasy Challenge deadline
Wolves v Newcastle
Finally, the match at Molineux, where five of their previous six meetings have ended as a score draw.
Predicting Newcastle’s starting full-backs could be tricky, but at least Fabian Schar (£5.4m) is now back from a ban.
He bagged four goals last season but comes with a hefty price tag. Rayan Ait-Nouri (£4.5m) is one to watch after he started Gameweek 3 as a left winger, providing he recovers from a knock.