A third successive victory for Sheffield United would take them up to fifth.
Brighton & Hove Albion are targeting their first win of 2020 but have lost only one of their last four.
Team news
Sheffield United manager Chris Wilder has reported no injury concerns and has a full squad to choose from.
Brighton will make a decision on Dale Stephens, Tariq Lamptey and Alexis Mac Allister. Jose Izquierdo remains sidelined.
Did you know?
Sheff Utd will host Brighton in the top flight for the first time ever. The two sides last met at Bramall Lane in the Championship in January 2006 with the Blades winning 3-1.
Only Wolverhampton Wanderers, with 18, have won more points from losing positions this season than Sheff Utd's 13. Meanwhile, Brighton have lost 14 points from winning positions, already more than in either of their previous campaigns.
There have been just 30 changes to the Blades' starting XI in the Premier League this season, fewer than any other side. They are also the only team to have started every match with the same formation, 3-5-2.
Brighton are looking for their first Premier League away win against a promoted side, at the seventh attempt.
Match officials
Referee: Graham Scott. Assistants: Neil Davies, Derek Eaton. Fourth official: David Webb. VAR: Darren Bond. Assistant VAR: Simon Beck.
