Arsenal will host FA Cup holders Manchester United in one of only two all-Premier League ties in the FA Cup third round.
All 20 Premier League clubs learned on Monday their opponents for the ties to be played over the weekend of 11 January.
It will be the 17th occasion that 14-time winners Arsenal and Man Utd, who have lifted the FA Cup 13 times, have met in the competition, including the 1979 and 2005 finals, which were both won by the Gunners.
Mikel Arteta and new Man Utd head coach Ruben Amorim face each other in the Premier League this Wednesday night at Emirates Stadium in a precursor for their FA Cup encounter.
In the other all-Premier League tie, seven-time FA Cup winners Aston Villa host West Ham United. The clubs have met three times in the competition, Villa winning twice and losing once.
Premier League leaders Liverpool have been drawn at home to League Two Accrington Stanley, and Manchester City welcome Salford City, who have enjoyed a meteoric rise from non-league to League Two since Man Utd's "Class of '92" players Nicky Butt, Gary Neville, Phil Neville, Ryan Giggs and Paul Scholes, got involved in 2014.
Tottenham Hotspur make the trip to Tamworth, one of only two non-league clubs remaining in the competition, while Newcastle United are at home to League Two newcomers Bromley, managed by former Crystal Palace goalkeeper Andy Woodman.
It could prove to be a family affair at Goodison Park where Everton's 39-year-old defender Ashley Young may potentially line up against his son Tyler, 18, who plays for Peterborough United, after the Toffees were drawn at home to the League One side.
FA Cup third round fixtures
AFC Bournemouth v West Brom
Arsenal v Man Utd
Aston Villa v West Ham
Birmingham City v Lincoln City
Brentford v Plymouth Argyle
Bristol City v Wolverhampton Wanderers
Chelsea v Morecambe
Coventry City v Sheffield Wednesday
Crystal Palace v Stockport County
Everton v Peterborough Utd
Exeter City v Oxford Utd
Fulham v Watford
Hull City v Doncaster Rovers
Ipswich Town v Bristol Rovers
Leeds Utd v Harrogate Town
Leicester City v QPR
Leyton Orient v Derby County
Liverpool v Accrington Stanley
Mansfield v Wigan
Man City v Salford City
Middlesbrough v Blackburn
Millwall v Dagenham & Redbridge
Newcastle v Bromley
Norwich City v Brighton & Hove Albion
Nottingham Forest v Luton Town
Preston v Charlton
Reading v Burnley
Sheffield Utd v Cardiff City
Southampton v Swansea City
Sunderland v Stoke City
Tamworth v Spurs
Wycombe Wanderers v Portsmouth
The third round matches come after a period of 70 Premier League fixtures in the space of 35 days, beginning with the start of Matchweek 14 on Tuesday 3 December, and ending with the final fixture of Matchweek 20 on Monday 6 January.
That period includes Man City v Man Utd in a Premier League match on Sunday 15 December.
Other dates to note
Before the FA Cup third round, the first legs of the EFL Cup semi-finals are scheduled for 8 January.
The quarter-finals of the EFL Cup are Arsenal v Crystal Palace, Newcastle v Brentford, Southampton v Liverpool and Spurs v Man Utd, due to be played on the 18 and 19 December.
PL matches either side of FA Cup and EFL Cup
29 December
Leicester v Man City
Crystal Palace v Southampton
Everton v Nott'm Forest
Fulham v AFC Bournemouth
Spurs v Wolves
West Ham v Liverpool
30 December
Aston Villa v Brighton
Ipswich v Chelsea
Man Utd v Newcastle
1 January
Brentford v Arsenal
4 January
Spurs v Newcastle
Aston Villa v Leicester
AFC Bournemouth v Everton
Crystal Palace v Chelsea
Man City v West Ham
Southampton v Brentford
Brighton v Arsenal
5 January
Fulham v Ipswich
Liverpool v Man Utd
6 January
Wolves v Nott'm Forest
8 January
EFL Cup semi-finals
Weekend of 11 January
FA Cup third round
14 January
Brentford v Man City
Chelsea v AFC Bournemouth
West Ham v Fulham
Nott'm Forest v Liverpool
15 January
Everton v Aston Villa
Leicester v Crystal Palace
Newcastle v Wolves
Arsenal v Spurs
16 January
Ipswich v Brighton
Man Utd v Southampton