There are three confirmed all-Premier League ties in the FA Cup fifth round, including holders Manchester United at home to Fulham.
The Cottagers are the third Premier League opponent for the Red Devils, who have overcome Arsenal and Leicester City so far in this season's competition.
Fulham will be hoping it's third time lucky against Man Utd this season, having suffered 1-0 defeats in both league meetings.
Elsewhere, EFL Cup finalists Newcastle United welcome Brighton & Hove Albion to St James' Park hoping to avenge a 1-0 loss when the two sides last met on Tyneside in October, while AFC Bournemouth host Wolverhampton Wanderers with the Cherries seeking to reach the quarter-finals for only the third time in the club's history.
There could be a fourth all-Premier League tie if Nottingham Forest win their fourth-round match at Exeter City on Tuesday night. Their reward would be a home meeting with Ipswich Town.
FA Cup fifth-round fixtures
Preston v Burnley
Aston Villa v Cardiff
Crystal Palace v Millwall
Manchester United v Fulham
Newcastle United v Brighton & Hove Albion
AFC Bournemouth v Wolverhampton Wanderers
Manchester City v Plymouth
Exeter/Nottingham Forest v Ipswich Town
The fifth-round matches will take place on the weekend of 1 March, after Matchweek 27 and before Matchweek 28 in the Premier League.
