After Liverpool's UEFA Champions League exit, football writer Ben Bloom looks at this week's other European matches featuring Premier League sides and what we can expect from them.
After heading off on their travels around the continent last week, the Premier League contingent return to home soil for their last-16 second legs in the UEFA Europa League and UEFA Conference League.
As well as looking to secure a quarter-final berth, the teams will also be playing to help the Premier League earn an additional spot in next season’s Champions League.
Here is all you need to know about the crucial second legs.
Europa League
Manchester United v Real Sociedad (agg: 1-1)
13 March, 20:00 GMT
Man Utd remain favourites to reach the Europa League's last eight, but there was a sense of what might have been after last week’s trip to Spain.
The Premier League side were comfortable for more than an hour against a team who have not progressed beyond this stage of any European competition since 1989.
Joshua Zirkzee’s first European goal for United gave the visitors a deserved lead, and Andre Onana did not have a save to make until a handball decision against Bruno Fernandes gifted Real Sociedad a penalty, converted by Mikel Oyarzabal.
Thereafter, the hosts looked the far more threatening side, with Onana required to keep things level by producing a couple of wonderful saves.
United’s problems were nothing new. Deploying a front three of Rasmus Hojlund, flanked by Zirkzee and Alejandro Garnacho, they repeatedly failed to find the killer final pass and/or finish off their moves.
"It is clear we have to be more clinical," said Ruben Amorim. "We’re creating chances. Sometimes you don’t see that because we manage not to shoot. Sometimes we are missing something."
Amorim also believes that a win for Man Utd at Old Trafford will give "more energy" in the final 10 matches of the Premier League campaign.
"It’s not [a win] going to change a lot the idea for the next season but it will give us more energy to finish the season in a different way," he added.
"So again, it’s going to be a really important game for us."
Yoro and Maguire unavailable
Amorim will be unable to call on the services of Leny Yoro on Thursday, the defender sustaining a foot injury against Arsenal on Sunday.
"Mason Mount is too soon," added Ruben. "Leny [Yoro] is out. Harry Maguire cannot play this one. I hope to have him for Sunday [against his former club Leicester City in the Premier League].
"Manu [Ugarte] is in the squad and I think there is no-one returning."
Tottenham Hotspur v AZ Alkmaar (agg: 0-1)
13 March, 20:00 GMT
Like Man Utd, Spurs' hopes of salvaging anything from a disappointing season lie in this competition, and they face an uphill challenge after a limp display in the Netherlands.
That their deficit is no greater than one goal was rather fortunate, with Ange Postecoglou admitting that "the result was probably the best thing" to come from his side’s first-leg performance.
Lucas Bergvall was unlucky to slice an attempted clearance into his own net for the game’s only goal, but the visitors were second best throughout, managing just one late shot on target.
If Spurs are to stay in the competition, it will require wholesale improvements all over the pitch. "It wasn’t good," admitted Postecoglou.
The head coach, who declared in pre-season that he tends to win trophies in his second season, was questioned about his comment in Wednesday's media conference.
"If that doesn’t happen this year, then I can’t say that any more," said Postecoglou. "What am I supposed to say? I’ve always won in the second year; I have in the past, everywhere I’ve been, but here (at Tottenham) it won’t happen.
"Is that what people want to hear? People can twist these things, use them, and you know what, maybe we defy all the odds and we do win something."
Danso misses out
Handily, the Spurs head coach will have some additional firepower to call upon. Cristian Romero and Micky van de Ven may well reunite in central defence, while Dominic Solanke is available to lead the line after only being fit enough for a 17-minute substitute appearance in the first leg.
Mathys Tel was ineffective in that role in the first leg, taken off at half-time with Son Heung-min moved central. That shift had little positive impact though.
Defender Kevin Danso is ruled out of the return leg after sustaining a hamstring injury in Sunday's Premier League match against AFC Bournemouth.
"Kevin got a hamstring injury in the last game so he's out," explained Postecoglou. "It's hard to say [how long] at the moment. He felt it right at the end of the game so we'll see."
Conference League
Chelsea v Copenhagen (agg: 2-1)
13 March, 20:00 GMT
Such is Chelsea’s superior strength to almost every UEFA Europa Conference League opponent that Enzo Maresca was able to take a gamble in the opening leg against Copenhagen, see it fail, make a raft of subsequent alterations, and still register a relatively comfortable win.
It could, and probably should, have been by a wider margin, had they not allowed Gabriel Pereira to pull a late goal back for the hosts. But there was little in the first leg to suggest that Chelsea will face a major threat at Stamford Bridge this Thursday.
Maresca gave starts to the likes of Tyrique George, Kiernan Dewsbury-Hall and 17-year-old Shumaira Mheuka, in an experiment that did not pay off.
After his team failed to register a shot on target in the first half, Chelsea's head coach made a triple substitution at the break, resulting in goals from Reece James and Enzo Fernandez.
Trio to be monitored
A trio of Chelsea players - James, Cole Palmer and Christopher Nkunku - will all be assessed ahead of the Copenhagen match after suffering with illness this week.
"For Cole, Reece and Christo, today [Wednesday] has been first session [of the week]," said Maresca. "Yesterday they were not here and two days ago we had a rest. Today they trained with us, took part in the session, and we will see tomorrow if we can use some of them."
Maresca also confirmed that Malo Gusto remains sidelined along with longer-term absentees Marc Guiu, Nicolas Jackson and Noni Madueke.
