With only five chips available during the season, it is vital that Fantasy Premier League managers use them effectively.
The two Wildcards are particularly valuable, giving managers an opportunity in each half of the season to pick a brand new squad and plan for the weeks ahead.
The 2016/17 FPL champion Ben Crabtree, tends to use his first Wildcard at the same time in each campaign, five or six weeks in.
“Around that time you've got a feel for starting line-ups, which teams are looking good, which teams are looking like they might disappoint and also which players are just coming to the fore,” he says in the video above.
Utkarsh Dalmia concurs, stating: “I usually use my first Wildcard in the second international break of the season.
“For my second Wildcard, it’s usually around Gameweek 30 or 31, when we know when the Double Gameweek starts.”
Alternative view
Sam Bonfield has a different perspective on the first Wildcard and recommends holding it for as long as possible.
“That will set you up really nicely for the second part of the season, meaning you can hold your second Wildcard for that little bit longer too,” she says.
“Then when we get into those all-important weeks of blanks and Double Gameweeks, you have as many chips available as possible and you can build a team that's really focusing on those.”
All three experts agree that the Bench Boost and Triple Captain chips are most effective in a Double Gameweek, when players have two matches.
But Sam adds: “There’s always potential, particularly with the Triple Captain, to play it in a Gameweek where you have a particularly good player in a good run of form with a fantastic fixture.”
See: Sam Bonfield's GW1 team: You have to invest in Toney
See: Ben Crabtree's GW1 team: Havertz can enjoy breakout season
See: Utkarsh Dalmia's GW1 team: Fixtures key to Antonio appeal
See: Chuck Booth's GW1 team: Saint-Maximin backed over Toney
See: Neal Thurman's GW1 team: Double up on Liverpool defence
See: Holly Shand's GW1 team: Calvert-Lewin can start strongly again
See: Ben McNair's GW1 team: Back Dias for clean sheets
See: Pranil Sheth's GW1 team: Double up on Aston Villa
See: Tom Cantle's GW1 team: Smith Rowe and Harrison are bargains
Also in this series
Part 1: How to make a strong start
Part 2: Must-have players for 2021/22
Part 3: How to pick your captain